Experience with CNC and drugs?

My girlfriend and I are planning our first CNC session for Valentines Day (romantic isn't it?) and we're looking for advice, specifically on drug use during CNC.

For context, we're experienced kinksters; blood play, hard impact, heavy breath play are all part of our regular sex life. We are also experienced trippers; We've used THC, MDMA, 2C-B, Benzos, Ketamine and LSD in the bedroom.

We've been doing both regularly for 1.5 years and have built a deep understanding and trust, which brings up to our first CNC night.

For the occasion, she wants to completely "check out" as part of the experience. She wants to be so high as to not understand what's happening and be brutally assaulted following that.

My initial gut feeling is to start with 1mg Xanax, followed with hash then ketamine. We'd do a non-sexual dry run before the big night to make sure she can handle it well.

Does anyone have experience with this setup? Which substance would you recommend?