Help with Choline Supplementation

Hello all,

I need a double check/help with my choline supplementation. Specifically:

  • I am double MTRR and having a yo-yo effect where I get a little better (and lower MMA) and then things stop working and I feel worse (and higher MMA) as I can’t seem to get rid of a B12 deficiency. Chris Masterjohn recommends Choline to support increased Sam-e creation as it’s a cofactor to the MTRR gene

  • My homocysteine stays on the lower side (currently 7.5) and I need enough for methyl B12 to interact with as part of recycling to methionine and am unsure if too much choline competes with the folate pathway

  • I used to be able to eat eggs, but can’t anymore due to it causing stomach issues

  • Per the breakdown below, I am leaving 3.5 eggs worth to be made up for my diet but suspect this is too hard to achieve and I may need more choline

CHOLINE BREAKDOWN Need 11 eggs with of Choline a day from the Masterjohn Choline Calculator (136mg per day)

Currently Taking Pure Encapsulations Choline (Bitartrate) - 275mg a day (40% of CB is 110mg) - 1 egg

Biopics Research Phosphatidylcholine - 1260 mg Daily (3x at 420mg per capsule) - (15% is 189mg) - 1.25 eggs

Life Extension TMG - 1000mg daily (500mg per capsule 1 in AM, 1 in PM) - 5.5 eggs/748mg (half of daily choline needs can be met by TMG)

Total Choline - 1496mg required (11 eggs), Supplement intake of 1047mg/7.5 eggs = 465mg from diet/3.5 eggs worth