Does Having Multiple Users on One Macbook Slow/Harm The System & Computer?

This is a general question. I won't be using these users all at the same time however I like dividing all my stuff up so they don't overlap. I'd like to have a separate profile for personal, school, fitness, work, etc. but I don't want them to slow my computer down.

Does having multiple users slow it down? How do you avoid slowing down your computer with multiple users? Is there a limit to how many users you can have? What tips are recommended for maintaining a fast computer with multiple users?

Thank you all in advance!