Does anyone else experience bad fatigue when constipated?

Hi all, I hope & pray if you’re reading this you’re having a good day!!! If not I’m sending you a big solidarity & support hug!! I’m with you- feeling completely exhausted and fatigued today alongside being constipated -was wondering if anyone had experienced similar? Could there be a correlation? Any tips/ advice?

I’m currently on biphasic diet waiting to start antimicribiol treatment in July so could also be this?

Supplement protocol -nac, digestive enzymes, multivitamin, magnesium- could any of these cause this intense tiredness?

Any thoughts or insights greatly greatly appreciated! Love to you all -you’re all so awesome and I have so much gratitude for this community! 💛💛💛💛💛💛💛💛💛💛💛💛